法医学杂志

法医学杂志 ›› 2020, Vol. 36 ›› Issue (4): 507-513.DOI: 10.12116/j.issn.1004-5619.2020.04.015

• 论著 • 上一篇    下一篇

应用颅缝薄层CT扫描推断汉族成人年龄

裘诗文， 涂梦， 范飞， 占梦军， 董晓爱， 张奎， 邓振华   

  1. 四川大学华西基础医学与法医学院，四川 成都 610041
  • 发布日期:2020-08-25 出版日期:2020-08-28
  • 通讯作者: 张奎，男，副教授，主要从事法医学教学、科研和鉴定；E-mail：newman-zhk@163.com 邓振华，男，教授，主要从事法医临床学和法医影像学研究；E-mail：dengzhenhua@scu.edu.cn
  • 作者简介:裘诗文（1996—），男，硕士研究生，主要从事法医临床学研究；E-mail：1475094363@qq.com
  • 基金资助:
    国家自然科学基金面上资助项目（81971801）

Age Estimation in Han Adults by Thin-Layer CT Scan of Cranial Sutures

QIU Shi-wen, TU Meng, FAN Fei, ZHAN Meng-jun, DONG Xiao-ai, ZHANG Kui, DENG Zhen-hua   

  1. West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China
  • Online:2020-08-25 Published:2020-08-28

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摘要： 目的 应用薄层CT扫描技术探讨颅缝愈合程度在法医学成人年龄推断中的价值，建立汉族成人年龄推断模型。 方法 收集20~70岁健康四川汉族成人头部薄层CT样本220例（男女性各110例），并从中随机抽取20例（男女性各10例）作为验证样本。将矢状缝、左右侧冠状缝、左右侧人字缝分别平均分为两段，每段再均分成10个层面并获取对应的多平面重建（multiplanar reformation，MPR）图像，根据MPR图像中的颅缝愈合状况将其划分为1~7级，分析各颅缝愈合程度与年龄的相关性，建立年龄推断回归方程。 结果 矢状缝、左右侧冠状缝、左右侧人字缝愈合等级均与年龄呈正相关。回归方程中男性决定系数（R2）为0.419，女性R2为0.589，总体R2为0.522。验证检验结果显示，男性平均绝对误差（mean absolute error，MAE）为6.39岁，女性MAE为6.16岁，总体MAE为6.29岁。 结论 应用颅缝薄层CT扫描技术进行成人年龄推断具有较高的准确性，可根据颅缝愈合程度推断汉族成人年龄。

关键词: 法医人类学, 颅缝, 计算机体层成像, 薄层扫描, 多平面重建, 年龄推断, 汉族

Abstract:  Objective To explore the value of degree of cranial suture closure in forensic adult age estimation by thin-layer CT scan and establish an adult age estimation model of the Han nationality. Methods Thin-layer CT scan samples of the heads of 220 healthy Sichuan Han adults （110 males, 110 females） aged 20 to 70 were collected, of which 20 samples （10 males, 10 females） were randomly selected as test samples. The sagittal suture, coronal suture （both left and right） and lambdoid suture （both left and right） were respectively and equally divided into 2 segments, and every segment was equally divided into 10 layers and the corresponding multiplanar reformation （MPR） images were selected. The closure of cranial sutures on MPR images was classified into the grades 1-7. The correlations between cranial sutures and age were analyzed to build regression equation for age estimation. Results The degree of closure of sagittal suture, coronal suture （both left and right） and lambdoid suture （both left and right） was positively correlated with age. The coefficient of determination （R2） of regression equation was 0.419 in males, 0.589 in females, and 0.522 in all samples. The results of the verification test showed that the mean absolute error （MAE） was 6.39 years in males, 6.16 years in females, and 6.29 years in all samples. Conclusion There was a higher accuracy in adult age estimation by thin-layer CT scan of cranial sutures. The age of Han nationality adults can be estimated by the degree of cranial sutures closure.

Key words: forensic anthropology, cranial sutures, computed tomography, thin slice scan, multiplanar reformation, age estimation, Han nationality