Journal of Forensic Medicine

法医学杂志 ›› 2019, Vol. 35 ›› Issue (5): 602-606.DOI: 10.12116/j.issn.1004-5619.2019.05.017

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Advancements in Single-cell Sequencing and the Prospect of Its Forensic Application

CHEN Man1,2, YANG Ya-ran1, WU Hui-juan3,4, YAN Jiang-wei1,2   

  1. 1. Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; 2. University of Chinese Academy of Sciences, Beijing 100049, China; 3. Beijing Center for Physical and Chemical Analysis, Beijing 100094, China; 4. Beijing Engineering Technology Research Centre of Gene Sequencing and Gene Function Analysis, Beijing 100094, China
  • Online:2019-10-25 Published:2019-10-28

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Abstract: Single-cell sequencing is a technique that analyzes DNA and RNA sequences on the cellular level with next generation sequencing. The ultra high resolution of single-cell sequencing provides new perspectives and opens new frontiers for our understanding of many areas of life sciences, including forensic genome. This paper summarizes the recent advancements in single-cell sequencing and the prospect of its forensic application.

Key words: forensic genetics, single-cell sequencing, genome, review