Correlation Analysis and Comparison of Adult CE-Chirp ABR Response Threshold and Pure Tone Hearing Threshold

doi:10.12116/j.issn.1004-5619.2021.210101

Abstract

Abstract:

Objective To study the application of CE-Chirp in the evaluation of hearing impairment in forensic medicine by testing the auditory brainstem response （ABR） in adults using CE-Chirp to analyze the relationship between the V-wave response threshold of CE-Chirp ABR test and the pure tone hearing threshold. Methods Subjects （aged 20-77 with a total of 100 ears） who underwent CE-Chirp ABR test in Changzhou De’an Hospital from January 2018 to June 2019 were selected to obtain the V-wave response threshold， and pure tone air conduction hearing threshold tests were conducted at 0.5， 1.0， 2.0 and 4.0 kHz， respectively， to obtain pure tone listening threshold. The differences and statistical differences between the average pure tone hearing threshold and V-wave response threshold were compared in different hearing levels and different age groups. The correlation， differences and statistical differences between the two tests at each frequency were analyzed for all subjects. The linear regression equation for estimating pure tone hearing threshold for all subjects CE-Chirp ABR V-wave response threshold was established， and the feasibility of the equation was tested. Results There was no statistical significance in the CE-Chirp ABR response threshold and pure tone hearing threshold difference between different hearing level groups and different age groups （P>0.05）. There was a good correlation between adult CE-Chirp ABR V-wave response threshold and pure tone hearing threshold with statistical significance （P<0.05）， and linear regression analysis showed a significant linear correlation between the two （P<0.05）. Conclusion The use of CE-Chirp ABR V-wave response threshold can be used to evaluate subjects’ pure tone hearing threshold under certain conditions， and can be used as an audiological test method for forensic hearing impairment assessment.

Key words: forensic medicine, CE-Chirp, auditory brainstem response, pure tone hearing threshold, V-wave response threshold, hearing impairment

CLC Number:

He-ying CHENG, Yun-ge ZHANG, Yan CHEN, Sun YIN, Ming LÜ, Chun-xiao LI. Correlation Analysis and Comparison of Adult CE-Chirp ABR Response Threshold and Pure Tone Hearing Threshold[J]. Journal of Forensic Medicine, 2024, 40(1): 15-19.

Figures/Tables 4

Tab. 1 Comparison of CE-Chirp ABR V-wave response threshold and average pure tone hearing threshold for individuals with different hearing levels

听力/dB HL	耳数	CE-Chirp ABR V波反应阈/dB nHL	平均纯音听阈^1）/dB HL	差值^2）/dB HL
<26	29	17.93±5.80	14.22±5.07	3.71±5.51
26~<41	18	38.33±10.85	33.54±3.59	4.79±10.33
41~<61	21	57.85±10.07	51.52±5.88	6.61±7.21
61~<81	23	72.39± 9.77	69.67±6.03	2.72±7.93
≥81	9	87.78±10.30	89.58±7.04	-1.85±8.04

Tab. 2 Comparison of CE-Chirp ABR V-wave response threshold and average pure tone hearing threshold in different age groups

年龄段/周岁	耳数	CE-Chirp ABR V波反应阈/dB nHL	平均纯音听阈^1）/dB HL	差值^2）/dB HL
20~29	22	25.45±20.35	22.78±11.55	2.67±5.06
>29~39	9	41.11±32.86	34.58±27.16	6.53±9.41
>39~49	19	49.21±24.51	46.58±22.94	2.63±9.13
>49~59	31	59.03±21.96	55.00±23.07	4.03±7.63
>59~69	13	63.85±13.41	60.48±16.52	3.37±10.18
>69	6	59.17±19.60	52.08±21.83	7.09±9.83

Tab. 3 The correlation between CE-Chirp ABR V-wave response threshold and pure tone hearing threshold in all subjects

测试频率	CE-Chirp ABR V波反应阈/ （ $x ¯$ ±s，dB nHL）	纯音听阈值/ （ $x ¯$ ±s，dB nHL）	差值^1）/ （ $x ¯$ ±s，dB nHL）	相关系数	t值	P值
0.5 kHz	48.80±25.71	37.90±21.86	10.90±14.30	0.830 8	7.58	<0.05
1.0 kHz	48.80±25.71	40.65±25.40	8.15±12.18	0.886 5	6.66	<0.05
2.0 kHz	48.80±25.71	46.65±29.03	2.15±11.12	0.924 6	1.92	<0.05
4.0 kHz	48.80±25.71	54.85±32.05	-6.05±12.01	0.937 0	-5.01	<0.05
中低频	48.80±25.71	39.28±23.65	9.53±12.38	0.876 8	7.66	<0.05
中高频	48.80±25.71	59.75±30.85	-1.95±9.90	0.943 8	-1.96	<0.05
言语频率	48.80±25.71	45.01±28.08	3.79±8.01	0.952 7	4.71	<0.05

Tab. 3 The correlation between CE-Chirp ABR V-wave response threshold and pure tone hearing threshold in all subjects

测试频率	CE-Chirp ABR V波反应阈/ （ $x ¯$ ±s，dB nHL）	纯音听阈值/ （ $x ¯$ ±s，dB nHL）	差值^1）/ （ $x ¯$ ±s，dB nHL）	相关系数	t值	P值
0.5 kHz	48.80±25.71	37.90±21.86	10.90±14.30	0.830 8	7.58	<0.05
1.0 kHz	48.80±25.71	40.65±25.40	8.15±12.18	0.886 5	6.66	<0.05
2.0 kHz	48.80±25.71	46.65±29.03	2.15±11.12	0.924 6	1.92	<0.05
4.0 kHz	48.80±25.71	54.85±32.05	-6.05±12.01	0.937 0	-5.01	<0.05
中低频	48.80±25.71	39.28±23.65	9.53±12.38	0.876 8	7.66	<0.05
中高频	48.80±25.71	59.75±30.85	-1.95±9.90	0.943 8	-1.96	<0.05
言语频率	48.80±25.71	45.01±28.08	3.79±8.01	0.952 7	4.71	<0.05

Tab. 4 Linear regression equation between CE-Chirp ABR V-wave response threshold and pure tone hearing threshold at various frequencies for all subjects

测试频率	线性回归方程	P值
0.5 kHz	y=0.700 9x+3.696 6	<0.05
1.0 kHz	y=0.876 2x-2.108 4	<0.05
2.0 kHz	y=1.044 5x-4.323 5	<0.05
4.0 kHz	y=1.168 4x-2.169 5	<0.05
中低频	y=0.794 1x+0.788 5	<0.05
中高频	y=1.150 6x-3.236 4	<0.05
言语频率	y=0.947 5x-1.297 8	<0.05

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