Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis

doi:10.12116/j.issn.1004-5619.2023.530210

Abstract

Abstract:

Tri-allelic pattern in autosomal STR is a common abnormal typing phenomenon in forensic DNA analysis, which brings difficulties and uncertainties to the evaluation of the evidence weight in actual cases. This paper reviews the types, formation mechanism, occurrence frequency, genetic pattern and quantitative evaluation of evidence of the tri-allelic pattern in autosomal STR in forensic DNA analysis. This paper mainly explains the formation mechanism and genetic patterns based on different types of tri-allelic pattern. This paper also discusses the determination of tri-allelic pattern and the quantitative method of evidence evaluation in paternity testing and individual identification. This paper aims to provide references for scientific and standardized analysis of this abnormal typing phenomenon in forensic DNA analysis.

Key words: forensic genetics, DNA, autosome, short tandem repeats, tri-allelic pattern, review

CLC Number:

Xiao-yan MA, Hong-yu SUN, Qing LI. Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis[J]. Journal of Forensic Medicine, 2023, 39(3): 240-246.

Figures/Tables 2

References 36

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