›› 2001, Vol. 0 ›› Issue (4): 196-197.

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Fos expression in rat skin after different incised wound healing interval

LIU NING-GUO1,ZHAO ZI-QIN2,GU YUN-JU2,ET AL. (1. INSTITUTION OF FORENSIC SCIENCES OF MINISTRY OF JUSTICE,SHANGHAI 200063; 2.DEPARTMENT OF FORENSIC MEDICINE, MEDICAL CENTER OF FUDAN UNIVERSITY, SHANGHAI 200032)   

  • Online:2001-08-25 Published:2001-08-28

Abstract: Objective To investigate the expression of c-fos in rats' skin during wound healing. Methods Immunohistochemistry was conducted on parafin section from incised wounding model of rat skin. Results Fos protein improved from the time of 10 min after wounding in the wound edge, then it reached peak at 3h. 24h after injury, the quantity of Fos expression had no difference with that of normal skin. Conclusion Fos is sensitive after wound, but should be used with other criteria in wounding interval estimation as it's unstediness.

Key words: Fos, immidiate earlly gene, wounding interval estimation, incised wound