Immunohistochemical study with depletion of cardiac troponin T in rats on early myocardial ischaemia

Abstract

Abstract: Objective To study the depletion of cardiac troponin T in Rats of early myocardial ischaemia. Methods Immunohistochemical method (LSAB) was used and the depletion area of CTnT in myocardial ischaemia were measured by the computer image analysis. Results There is obviously depletion of CTnT after 15 min in myocardial ischaemia of rats, the mean of CTnT depletion of myocardial ischaemic group is significant difference compared with that of the control group(P< 0.01), and the depletion area increased with the prolongagtion of ischaemic time. Conclusion The depletion of CTnT is one of sensitive signs of early myocardial ischaemia.

Key words: early myocardial ischaemia, cardiac troponin T, immunohistochemistry, image analysis system

DENG DA-ZHONG;CHEN YU-CHUAN;HU BIN-JIE;ET AL. (.DEPARTMENT OF CRIMINAL TECHNIQUE;GUANGDONG POLICE COLLEGE;GUANGZHOU 0;.DEPARTMENT OF FORENSIC PATHOLOGY;SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES;GUANGZHOU 00). Immunohistochemical study with depletion of cardiac troponin T in rats on early myocardial ischaemia[J]. , 2002, 0(1): 12-14+6.

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Immunohistochemical study with depletion of cardiac troponin T in rats on early myocardial ischaemia

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