Abstract: Objective To investigate the relationship between tryptase in serum and anaphylaxis.Methods The concentrations of tryptase in the sera of heart blood in three persons died from anaphylaxis shock were detected by ELISA.The first sample was obtained from a man,aged38,died of injecting Amikacin.The second sample was obtained from a man,aged42,died of injecting Cephradine.The third sample was from a woman,aged39,died of injecting Lincomycin.All samples were stored in-20℃.Results The concentrations of tryptase in sera were52ng/ml,121ng/ml and0.73ng/ml.It was unknown why the concentration of tryptase in the third sample was normal.Conclution In fetal anaphylaxia reaction tryptase measurement is a useful indicator,but the diagnosis is not to be based on the test alone.

Key words: tryptase, anaphylaxis shock, ELISA