Ion-pair Solid-phase Extraction(SPE) and HPLC Analysis of Paraquat in Biological Sample

›› 2005, Vol. 0 ›› Issue (2): 121-123.

Ion-pair Solid-phase Extraction(SPE) and HPLC Analysis of Paraquat in Biological Sample

WANG RUI-HUA1, SU SHAO-MING2, QIN GUANG-MING1, ET AL. (1. FORENSIC MEDICINE SCHOOL OF KUNMING MEDICAL COLLEGE, KUNMING 650031,CHINA; 2. CRIMINAL SCIENCE AND TECHNOLOGY INSTITUTE OF YUXI PUBLIC SECURITY BUREAU ,YUXI 650031,CHINA)

Online:2005-04-25 Published:2005-04-28

Abstract

Abstract: Objective To establish an HPLC method for the determination of Paraquat in biological samples. Methods Paraquat in biological samples was extracted by C18 columns which were pre-treated with cetyl-trimethyl ammonium bromide(CTAB) and soudium dodecyl sulphate(SDS), and analysed by HPLC/DAD. Results The detection limit of the method was 1ng·mL-1,and the average recoveries were 81%～94%. Conclusion The method can be used to analysis of paraquat in biological samples.

Key words: paraquat, biological sample, ion-pair, solid-phase extraction, HPLC/DAD

WANG RUI-HUA;SU SHAO-MING;QIN GUANG-MING;ET AL. (. FORENSIC MEDICINE SCHOOL OF KUNMING MEDICAL COLLEGE;KUNMING 00;CHINA;. CRIMINAL SCIENCE AND TECHNOLOGY INSTITUTE OF YUXI PUBLIC SECURITY BUREAU;YUXI 00;CHINA). Ion-pair Solid-phase Extraction(SPE) and HPLC Analysis of Paraquat in Biological Sample[J]. , 2005, 0(2): 121-123.

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Ion-pair Solid-phase Extraction(SPE) and HPLC Analysis of Paraquat in Biological Sample

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