Forensic Pathological Significance of Immunohistochemical Study with CX43 In Rats on Early Myocardial Ischaemia

Abstract

Abstract: Objective To explore one of evidence for pathologic diagnosis of early myocardial ischaemia. Methods Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry. Results It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group. Conclusion The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.

Key words: myocardial ischaemia, immunohistochemistry, CX43

JIN LI-FANG;CHEN MING-FANG;ZHENG QIANG;XU JING-YAO;SHEN YONG-HAO;ZHU YOU-FA (.INSTITUTE OF CRIMINAL SCIENCE;HANGZHOU PUBLIC SECURITY BUREAU;HANGZHOU 00 CHINA;.TRAFFIC POLICE;HANGZHOU PUBLIC SECURITY BUREAU;HANGZHOU 00;CHINA;.IN. Forensic Pathological Significance of Immunohistochemical Study with CX43 In Rats on Early Myocardial Ischaemia[J]. , 2006, 0(6): 411-412+.

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Forensic Pathological Significance of Immunohistochemical Study with CX43 In Rats on Early Myocardial Ischaemia

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