A Study in Extraction Method of Buprenorphine in Urine

Abstract

Abstract: Objective The extraction method for separating buprenorphine from urine was described.Methods Buprenorphine was extracted with chloroform at pH7 or with SPE(extracted by organic support 401 at pH10.8,then eluted with chloroform),finally determined by GC-NPD.Results The extracted yields of the analyte in specimens were 86.6% by solution-phase extraction and 83.0% by solid-phase extraction(SPE) respectively.Conclusion These two methods are simple and accurate for separating buprenorphine from urine.

Key words: buprenorphine, solid-phase extraction, solution-phase extraction, urine

LIU DONG-XIAN;HE JIANG-NAN(DEPARTMENT OF CRIMINAL TECHNOLOGY;HUNAN PUBLIC SECURITY COLLEGE;CHANGSHA 0;CHINA). A Study in Extraction Method of Buprenorphine in Urine[J]. , 2007, 0(4): 292-294.

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A Study in Extraction Method of Buprenorphine in Urine

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