Journal of Forensic Medicine ›› 2023, Vol. 39 ›› Issue (2): 176-185.DOI: 10.12116/j.issn.1004-5619.2022.320801

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Research Progress on Biological Matrix Reference Materials in Forensic Toxicology

Hang CHEN1(), Jing HU1,2(), Zheng QIAO1, Hong-xiao DENG1, Min LÜ1, Wei LIU1()   

  1. 1.Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
    2.School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
  • Received:2022-08-10 Online:2023-06-06 Published:2023-04-25
  • Contact: Wei LIU

Abstract:

Biological matrix reference material is a reference material that combines the target material with the biological matrix. The biological matrix reference material has higher consistency with the authentic specimens in forensic toxicology, and its application has a positive effect on improving the accuracy of test results. This paper reviews the research on the matrix reference materials corresponding to three common biological test materials (blood, urine and hair). In order to provide reference for the development and application of biological matrix reference materials in forensic toxicology, this paper mainly introduces the research progress of preparation technology of biological matrix reference materials and some existing products and their parameters evaluation.

Key words: forensic medicine, toxicological analysis, matrix reference material, blood, urine, hair, review

CLC Number: