Journal of Forensic Medicine ›› 2025, Vol. 41 ›› Issue (5): 421-440.DOI: 10.12116/j.issn.1004-5619.2025.550704

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Precision Identification from a Multi-omics Perspective: Current Status, Challenges, and Prospects in Forensic Genetics ZHU Bo-feng

  

  1. School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China
  • Received:2025-07-31 Online:2026-01-27 Published:2025-10-25

Abstract:

Driven by the deep integration and continuous advancement of multi-omics technologies, forensic genetics has been rapidly transforming from traditional marker-based detection to more refined and intelligent approaches in recent years. Based on the relevant domestic and international research in the past six years (2020-2025), this paper systematically reviews the research progress and developmental trend of forensic genetics across major application areas: individual identification, kinship testing, tissue origin identification, biogeographical origin and individual phenotype identification, age estimation, and non-human biological evidence analysis. These insights aim to provide theoretical foundations and practical guidance for the advancement of precise forensic identification technologies, interdisciplinary integration, and the innovation of judicial evidence systems.

Key words: forensic genetics, individual identification, kinship identification, tissue origin identification, biogeographical origin identification, forensic DNA phenotyping, age estimation, non-human biological evidence, review

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