Application of VNTR D17S30 locus polymorphism in the paternity test

Abstract

Abstract: A sensitive and rapid PCR-based technique was adoptedto genotype the VNTR D17S30 locus. It was confirmedthrough the genetic analysis of 20 normal families thatthe inheritance of D17S30 locus coincides withMendelian law as simple co-dominant. Retrospective analysis of 100 Paternity cases demonstrated thatD17S30 locus could be used in forensic paternity test inour counts. The exclusion probability estimated fromallele frequencies of D17S30 locus (74.04%) does notdiffer significantly from the observed rate of exclusion(80.00%) in these cases. In all excluded paternity casesthere are two in which the exclusion evidence is solelyprovided by the D17530 locus.

Key words: VNTR D17S30, paternity test, probability of exclusion

FENG MINGLIANG;FENG ZHE LU QING. ZHANGZ-HANG;YANG YING;JI YUEHUA;CHEN RENBIAO (IMMUNO-GENTETICSLABORATORY;SHANGHAI INSTITUTUTE OF BLOOD TRANSFUSION;SHANGHAI BLOOD CENTER;SHANGHAI 000). Application of VNTR D17S30 locus polymorphism in the paternity test[J]. , 1998, 0(1): 8-9+61.

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Application of VNTR D17S30 locus polymorphism in the paternity test

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