法医学杂志

法医学杂志 ›› 2010, Vol. 26 ›› Issue (6): 418-420.DOI: 10.3969/j.issn.1004-5619.2010.06.004

• 论著 • 上一篇    下一篇

房室结纤维和脂肪增多与房室结动脉狭窄的关系

崔丽娟1，易旭夫2，陈晓刚2   

  1. （1. 遂宁市中心医院 病理科，四川 遂宁 629000； 2. 四川大学 华西基础医学与法医学院，四川 成都 610041）
  • 发布日期:2010-12-25 出版日期:2010-12-28
  • 通讯作者: 通信作者：易旭夫，男，副教授，主要从事法医病理学研究
  • 作者简介:崔丽娟（1982—），女，山西侯马人，硕士，主要从事病理学研究；E-mail：smileclj@126.com

Relationship between the Increase of Fibrous and Fatty in Atrioventricular Node and Narrowing of the Atrioventricular Node Artery

CUI LI-JUAN1, YI XU-FU2, CHEN XIAO-GANG2   

  1. （1. Department of Pathology, Suining Central Hospital, Sunning 629000, China; 2. West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China）
  • Online:2010-12-25 Published:2010-12-28

被引次数

16

摘要： 目的 探讨房室结纤维、脂肪含量与房室结动脉狭窄之间的关系，分析房室结内病理性纤维化和病理性脂肪浸润的原因。 方法 选取119例心源性猝死案例，用Image-pro plus图像分析软件检测组织切片，计算房室结面积，房室结动脉内径、房室结动脉管腔面积（lumen area，LA）、外周横截面积（perimeter area，PA），纤维组织面积和脂肪组织面积。将所有案例分为动脉狭窄组和正常对照组组，观察房室结动脉PA/LA值及房室结纤维及脂肪含量的改变。 结果 狭窄组房室结动脉PA/LA值在21～40岁最大，40岁以下两组房室结脂肪含量和总间质含量差异有统计学意义。 结论 房室结动脉狭窄与房室结间质含量增多有一定关系。

关键词: 法医病理学, 房室结, 间质细胞, 动脉狭窄

Abstract: Objective To explore relationship between increase of fibrous and fatty in atrioventricular node（AVN） and narrowing of the AVN artery. To analyze the cause of pathological fibrosis and fatty infiltration in AVN. Methods One hundred and nineteen cases of sudden cardiac death determined by autopsy were selected and the histological sections were examined with Image-pro plus software to calculate the AVN area, AVN artery inside-diameter, AVN artery lumen area（LA） , AVN artery perimeter area（PA）, fibrous area and fatty area. All cases were divided into two groups： narrowing of artery group and normal control group. The changes of the PA/LA value and the fibrous and fatty contents were evaluated. Results The PA/LA value is the highest in 21-40 age group. The difference of the fatty contents and total interstitial tissue was statistical significance in the two groups under 40 years of age. Conclusion There is some relationship between the narrowing of the AVN artery and the increase of interstitial contents in AVN.

Key words: forensic pathology, atrioventricular node, stromal cells, narrowing of the artery

中图分类号: