法医学杂志 ›› 2013, Vol. 29 ›› Issue (6): 405-408.DOI: 10.3969/j.issn.1004-5619.2013.06.002

• 论著 • 上一篇    下一篇

人体死亡后血液中生化指标的变化

邓恺飞1,黎世莹1,2,秦志强1,刘宁国1,邹冬华1,陈忆九1,黄  平1   

  1. (1. 司法部司法鉴定科学技术研究所 上海市法医学重点实验室,上海 200063; 2. 复旦大学上海医学院法医学系,上海 200032)
  • 发布日期:2013-12-25 出版日期:2013-12-28
  • 通讯作者: 黄平,男,博士,副研究员,副主任法医师,主要从事法医病理学研究;E-mail:huangpingifs@gmail.com
  • 作者简介:邓恺飞(1984—),男,上海人,技师,主要从事法医病理学研究;E-mail:cafe.deng@gmail.com
  • 基金资助:

    上海市法医学重点实验室资助项目(13DZ2271500)

Changes of Postmortem Human Blood Biochemical Indexes

DENG KAI-FEI1, LI SHI-YING1,2, QIN ZHI-QIANG1, LIU NING-GUO1, ZOU DONG-HUA1, CHEN YI-JIU1, HUANG PING1   

  1. (1. Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, P.R.China, Shanghai 200063, China; 2. Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China)
  • Online:2013-12-25 Published:2013-12-28

摘要: 目的 测定人体死亡后血液中生化指标的变化并进行分析。 方法 收集81例交通事故死亡后尸体锁骨下静脉血样,并采用罗氏cobas c311全自动生化分析仪检测血液中肝功能(ALT、AST、TBIL、DBIL)、肾功能(UA、Cr)、心功能(CK、CK-MB、LDH)、电解质(K+、Na+、Cl-)以及葡萄糖(GLU) 13项生化指标的变化,采用SPSS 17.0统计学软件进行描述性分析。 结果 生化指标中ALT、AST、CK、CK-MB、LDH、K+数值较活体正常参考值高、波动幅度较大。TBIL、DBIL、UA、Cr、Na+、Cl-、GLU数值相对稳定、波动幅度较小。 结论 人体死亡后血液生化指标中肝功能、肾功能、心功能、电解质以及葡萄糖等指标易受溶血、自溶等因素影响,表现为生化指标升高明显,尤以酶类为著,且标准差较大。

关键词: 法医病理学, 死后变化, 血液, 生化指标

Abstract: Objective To investigate and analyze the changes of postmortem human biochemical indexes. Methods Subclavian venous blood samples were collected from 81 cases of traffic fatalities. Thirteen blood biochemical indexes including liver function (ALT, AST, TBIL and DBIL), renal function (UA and Cr), cardiac function (CK, CK-MB and LDH), electrolytes (K+, Na+ and Cl-), and glucose (GLU) were tested by Roche cobas c311 automatic biochemical analyzer. The descriptive analysis was made by SPSS 17.0 statistical software. Results The values of ALT, AST, CK, CK-MB, LDH and K+ were higher than normal reference values with more fluctuations. The values of TBIL, DBIL, UA, Cr, Na+, Cl- and GLU were relatively stable with less fluctuations. Conclusion The postmortem human blood biochemical indexes of liver function, renal function, cardiac function, electrolytes and glucose could be affected by the factors, especially hemolysis and autolysis. The biochemical indexes, particularly enzymes, increased significantly with higher standard deviation.

Key words: forensic pathology, postmortem changes, blood, biochemical indexes

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