法医学杂志

法医学杂志 ›› 2016, Vol. 32 ›› Issue (1): 35-39.DOI: 10.3969/j.issn.1004-5619.2016.01.008

• 论著 • 上一篇    下一篇

正常人模式脉冲与模式翻转多焦视诱发电位的比较

朱镕霆，刘兴本，徐晓明，郑传斐   

  1. （中国医科大学法医学院法医临床教研室，辽宁 沈阳 110001）
  • 发布日期:2016-02-25 出版日期:2016-02-28
  • 通讯作者: 刘兴本，男，教授，主要从事法医学教学、科研及鉴定工作；E-mail：xbliu@mail.cmu.edu.cn
  • 作者简介:朱镕霆（1988—），女，硕士，主要从事法医学研究；E-mail：459829122@qq.com

Comparison of Pattern-pulse and Pattern-reversal Multifocal Visual Evoked Potentials in Normal Individuals

ZHU RONG-TING, LIU XING-BEN, XU XIAO-MING, ZHENG CHUAN-FEI   

  1. （Department of Forensic Medicine, China Medical University, Shenyang 110001, China）
  • Online:2016-02-25 Published:2016-02-28

摘要： 目的 比较正常人模式脉冲多焦视诱发电位（pattern-pulse multifocal visual evoked potential，PPmfVEP）与模式翻转多焦视诱发电位（pattern-reversal multifocal visual evoked potential，PRmfVEP）的优缺点，观察多焦视诱发电位（mfVEP）的双眼对称性。 方法 采用Vision Monitor多焦视觉电生理仪检测系统行mfVEP检查，应用t检验和方差分析对两种VEP的主波（P1）、波幅、信噪比及双眼对称性进行统计分析。 结果 PPmfVEP与PRmfVEP P1波幅和信噪比均在中央视野最大，并随离心度的增加呈减小趋势，下降速度由快渐趋平缓。在中央视网膜PPmfVEP波幅的变异系数明显小于PRmfVEP，而在周围视网膜则与之相反；PPmfVEP与PRmfVEP双眼对称象限的P1波幅及信噪比差异均无统计学意义（P>0.05），双眼同侧象限的波幅差异均大于对称象限。 结论 mfVEP能准确、客观地反映视网膜不同部位的视功能；PPmfVEP较PRmfVEP能更好地反映中央视网膜的视功能状况，而在周边视网膜没有优势；在中央视网膜，PPmfVEP较PRmfVEP稳定；而在外周视网膜，PRmfVEP较PPmfVEP稳定；mfVEP在同一个体双眼之间存在对称性。

关键词: 法医学；诱发电位, 视觉；模式翻转多焦视诱发电位；模式脉冲多焦视诱发电位

Abstract: Objective To compare pattern-pulse multifocal visual evoked potential （PPmfVEP） with pattern-reversal multifocal visual evoked potential （PRmfVEP）, and to investigate the symmetry of mfVEP between both eyes in normal individuals. Methods The multifocal Vision Monitor was used to observe the mfVEP. T-test and ANOVA were used to analyze P1 wave, amplitude and signal noise ratios （SNR） of two mfVEPs. Results The SNR and the P1 amplitude reached the maximum at the central visual field and decreased with the increase of eccentricity, and then decreased slowly. The amplitude of the PPmfVEP was significantly smaller than the PRmfVEP in the central retina, while in the peripheral retina the result was exactly the opposite. SNR and amplitude of the PRmfVEP showed no statistical difference in both eyes （P＞0.05）. The variance of the amplitude at the same side of visual field was larger than that at the symmetrical visual quadrant. Conclusion mfVEP can reflect the visual function in different parts of retina objectively and exactly. PPmfVEP reflect the vision function of the central retina better than PRmfVEP. The stability of PPmfVEP is better than PRmfVEP in the central retina, while the result is opposite in the peripheral retina. The mfVEP is symmetrical in both eyes of the same individual.

Key words: forensic medicine, evoked potentials, visual, pattern-pulse multifocal visual evoked potential, pattern-reversal multifocal visual evoked potential

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