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法医学杂志 2018, Vol. 34 Issue (1) :49-54    DOI: 10.3969/j.issn.1004-5619.2018.01.010
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玻璃体液检测技术在法医学死亡时间推断中的研究进展
段伟成,兰玲梅,郭亚东,扎拉嘎白乙拉,闫  杰,丁艳君,蔡继峰
中南大学基础医学院法医系,湖南 长沙 410013
Research Progress of Vitreous Humor Detection Technique on Estimation of Postmortem Interval
DUAN Wei-cheng, LAN Ling-mei, GUO Ya-dong, ZHA Lagabaiyila, YAN Jie, DING Yan-jun, CAI Ji-feng
Department of Forensic Science, School of Basic Medical Science, Central South University, Changsha 410013, China

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摘要 死亡时间(PMI)的判定在法医学研究及检案工作中一直占据极其重要的地位。玻璃体液因其独特的解剖学位置,被认为能较好地用于PMI推断,且引起了学者的兴趣,并对此展开了较多研究。目前,针对玻璃体液的检测技术在不断发展完善,并已被逐渐应用于法医学,同时利用玻璃体液进行PMI推断的研究也在不断深入。本文对目前已报道的不同玻璃体液检测技术、仪器,如离子选择性电极技术、毛细管离子分析技术、光谱法、色谱法、纳米传感技术、全自动生化分析仪、流式细胞仪等,以及近年基于此展开的PMI推断研究的相关进展进行了综述,同时分析其存在的问题,为学者们提供研究方向,以期使得玻璃体液分析在PMI推断中更加精确、实用。
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段伟成
兰玲梅
郭亚东
关键词法医病理学;玻璃体液;综述;死亡时间;色谱法   液相;光谱法   荧光     
Abstract: Estimation of postmortem interval (PMI) plays a crucial role in forensic study and identification work. Because of the unique anatomy location, vitreous humor is considered to be used for estima- ting PMI, which has aroused interest among scholars, and some researches have been carried out. The detection techniques of vitreous humor are constantly developed and improved which have been gradually applied in forensic science, meanwhile, the study of PMI estimation using vitreous humor is updated rapidly. This paper reviews various techniques and instruments applied to vitreous humor detection, such as ion selective electrode, capillary ion analysis, spectroscopy, chromatography, nano-sensing technology, automatic biochemical analyser, flow cytometer, etc., as well as the related research progress on PMI estimation in recent years. In order to provide a research direction for scholars and promote a more accurate and efficient application in PMI estimation by vitreous humor analysis, some inner problems are also analysed in this paper.
Keywordsforensic pathology   vitreous humor   review   postmortem interval   chromatography, liquid   spectrometry, fluorescence     
Fund:

国家自然科学基金资助项目(81772025);中南大学国家级大学生自由探索资助项目(201610533528)

Corresponding Authors: 丁艳君,女,博士,副教授,硕士研究生导师,主要从事法医毒物分析研究;E-mail:dingyanjun@csu.edu.cn    
About author: 段伟成(1995—),男,本科生,主要从事法医病理学研究;E-mail:18711092437@163.com
引用本文:   
段伟成, 兰玲梅, 郭亚东,等.玻璃体液检测技术在法医学死亡时间推断中的研究进展[J]  法医学杂志, 2018,34(1): 49-54
DUAN Wei-Cheng, LAN Ling-Mei, GUO Ya-Dong,et al..Research Progress of Vitreous Humor Detection Technique on Estimation of Postmortem Interval[J]  , 2018,34(1): 49-54
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