法医学杂志

法医学杂志 ›› 2026, Vol. 42 ›› Issue (1): 66-68.DOI: 10.12116/j.issn.1004-5619.2026.360302

• 前沿快报 • 上一篇    下一篇

合成药毒物：普瑞巴林

陈航(), 王鑫, 严慧, 向平()   

  1. 司法鉴定科学研究院 上海市法医学重点实验室 司法部司法鉴定重点实验室 上海市司法鉴定专业技术服务平台，上海 200063
  • 收稿日期:2026-01-04 发布日期:2026-04-28 出版日期:2026-02-25
  • 通讯作者: 向平
  • 作者简介:陈航（1988—），男，博士，副主任法医师，主要从事法医毒物学研究；E-mail：chenh@ssfjd.cn
  • 基金资助:
    国家重点研发计划资助项目(2024YFC3306602);中央级公益性科研院所资助项目(GY2025G-3);上海市法医学重点实验室资助项目(21DZ2270800);上海市标准化创新中心（司法鉴定）资助项目

Synthetic Drug： Pregabalin

Hang CHEN(), Xin WANG, Hui YAN, Ping XIANG()   

  1. Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
  • Received:2026-01-04 Online:2026-04-28 Published:2026-02-25
  • Contact: Ping XIANG

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摘要：

普瑞巴林是一种抑制性神经递质γ-氨基丁酸类似物，当前，与普瑞巴林误用或滥用有关的死亡案例呈增加趋势，亟须相关的法医毒物信息。本文基于国内外相关研究，系统梳理普瑞巴林的药理作用、毒性数据、中毒症状、体内过程以及已有各类典型案例的毒物分析数据，以期为法医学鉴定提供参考。

关键词: 法医学, 毒物分析, 普瑞巴林, 药理作用, 中毒症状, 体内过程

Abstract:

Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid. Currently, the number of deaths related to the misuse or abuse of pregabalin is gradually increa-sing, and there is an urgent need for relevant forensic toxicological information. Based on relevant do-mestic and international research, this article systematically reviews the pharmacological effects, toxicity data, poisoning symptoms, in vivo processes of pregabalin, as well as the toxicological data of various existing typical cases, with the aim of providing a reference for forensic identification.

Key words: forensic medicine, toxicological analysis, pregabalin, pharmacological effects, symptoms of poisoning, in vivo process

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