Study on distribution of alprazolam in poisoned rabbits

Abstract

Abstract: The distribution of clozapinc in the body of rabbits died of poison was studied by the method of TLC.The concentration of clozapine in blood. urine,bile,livers. kidneys. spleen. lungs.hearts and brainse were19.4±6.9, 50.2±12.6,75.9±12.5,25.9±4.0,34.0±4.7,13.3±2.2, 20.0±4.3, 5.0±2.3 and 43.6±43, 4ug/ml or ug/g.respectively. It is concluded that the Clozapine be not well-distribuled in poisoned rabbits. Blood. bile,urine.liver and spleen are better samples for the analysis of clozapine than others.

Key words: Clozapine, TLC, Poisoning, Distribution

YUN KEMING;LI GUIMING .(DEPARTMENT OF FOSRENSIC MEDICINE;SHANXI MEDICAL UNIVERSITY;SHANXI 0000). Study on distribution of alprazolam in poisoned rabbits[J]. , 1997, 0(1): 14-15+6.

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Study on distribution of alprazolam in poisoned rabbits

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