Abstract: Using GC/MS - SIM, we examined morPhine distribution in human bodies of 2 delayed death cases and analyzed content of morphine and 6 - acetylmorphine (MAM) in hair specimens of 7 cases. Afer hydrolysis and extraction, MoR and 6 - MAM were derived with acetic anhydride or BSTFA and then the derivatives were qualitatively and quantitatively analyzed by GC/MS SIM. The results indicated that urine, bile and liver were the best samples to reveal the heroin - related deaths. Hair analysis has its unique advantage for its long time of abusing monitor, compared to biological fluids.

Key words: GC/MS-SIM, biological fluid, tissue, hair, metabolite, derivative, 6-acetylmorphine morphine