Expression of c-jun Protein after Experimental Rat Brain Concussion

Abstract

Abstract: Objective To observe c-jun protein expression after rat brain concussion and explore the forensic pathologic markers following brain concussion.Methods Fifty-five rats were randomly divided into brain con-cussion group and control group.The expression of c-jun protein was observed by immunohistochemistry.Results There were weak positive expression of c-jun protein in control group.In brain concussion group,however,some neutrons showed positive expression of c-jun protein at 15 min after brain concussion,and reach to the peak at 3 h after brain concussion.Conclusion The research results suggest that detection of c-jun protein could be a marker to determine brain concussion and estimate injury time after brain concussion.

Key words: forensic pathology, brain concussion, proto-oncogene proteins c-jun, wound age, rats

WANG FENG;LI YONG-HONG(DEPARTMENT OF FORENSIC MEDICINE;WANNAN MEDICAL COLLEGE;WUHU 00;CHINA). Expression of c-jun Protein after Experimental Rat Brain Concussion[J]. , 2010, 0(1): 15-17.

[1]	Yong ZENG, Dong-hua ZOU, Ying FAN, Qing XU, Lu-yang TAO, Yi-jiu CHEN, Zheng-dong LI. Research Progress and Forensic Application of Human Vascular Finite Element Modeling and Biomechanics [J]. Journal of Forensic Medicine, 2023, 39(5): 471-477.
[2]	Yu-xin SUN, Xiao-juan GONG, Xiu-li HAO, Yu-xin TIAN, Yi-ming CHEN, Bao ZHANG, Chun-xia YAN. Screening of Genes Co-Associated with Sudden Infant Death Syndrome and Infectious Sudden Death in Infancy and Bioinformatics Analysis of Their Regulatory Networks [J]. Journal of Forensic Medicine, 2023, 39(5): 433-440.
[3]	Yu YANG, Fan-zhang LEI, Yu-you DONG, Jian-long MA, Qi-qiang SHI, Xue-song YE. Retrospective Analysis of Death Cases of Oral Diphenidol Hydrochloride Poisoning [J]. Journal of Forensic Medicine, 2023, 39(4): 393-398.
[4]	Qing-qing XIANG, Li-fang CHEN, Qin SU, Yu-kun DU, Pei-yan LIANG, Xiao-dong KANG, He SHI, Qu-yi XU, Jian ZHAO, Chao LIU, Xiao-hui CHEN. Research Progress on Microbial Community Succession in the Postmortem Interval Estimation [J]. Journal of Forensic Medicine, 2023, 39(4): 399-405.
[5]	Qin SU, Qian-ling CHEN, Wei-bin WU, Qing-qing XIANG, Cheng-liang YANG, Dong-fang QIAO, Zhi-gang LI. Metabonomics Analysis of Brain Stem Tissue in Rats with Primary Brain Stem Injury Caused Death [J]. Journal of Forensic Medicine, 2023, 39(4): 373-381.
[6]	Xu-dong ZHANG, Yao-ru JIANG, Xin-rui LIANG, Tian TIAN, Qian-qian JIN, Xiao-hong ZHANG, Jie CAO, Qiu-xiang DU, Jun-hong SUN. Postmortem Interval Estimation Using Protein Chip Technology Combined with Multivariate Analysis Methods [J]. Journal of Forensic Medicine, 2023, 39(2): 115-120.
[7]	Wu LONG, Peng-fei QU, Lin MA, Rui WANG, Yan-mei XI, Yu-hua LI, Sheng-jie NIE, Ting DUAN, Jin-liang DU, Xue TANG, Jing-feng ZHAO, Pu-ping LEI, Yue-bing WANG. Cytotoxicity of 4 Wild Mushrooms in a Case of Yunnan Sudden Unexplained Death [J]. Journal of Forensic Medicine, 2023, 39(2): 121-128.
[8]	Jun-wei GAO, Yang LU, Yan-jun LI, Dong-hua ZOU, Guang-long HE, Yan-bin WANG. Survey on the Construction Status of Forensic Virtual Autopsy Laboratory and the Applicability of Laboratory Accreditation [J]. Journal of Forensic Medicine, 2023, 39(2): 186-192.
[9]	Fang-Fang LIU, Hui WU, Wei WANG, Ying XIE. Changes of 1，5-AG in Vitreous Humor of Rabbit Cadavers with Hyperglycemic Metabolism [J]. Journal of Forensic Medicine, 2023, 39(1): 13-17.
[10]	Zhi-ling TIAN, Ruo-lin WANG, Jian-hua ZHANG, Ping HUANG, Zhi-qiang QIN, Zheng-dong LI, He-wen DONG, Dong-hua ZOU, Mao-wen WANG, Zhuo LI, Lei WAN, Xiao-tian YU, Ning-guo LIU. Comparison of CT Values between Thrombus and Postmortem Clot Based on Cadaveric Pulmonary Angiography [J]. Journal of Forensic Medicine, 2023, 39(1): 7-12.
[11]	Jia-yi WU, You-jia YU, Kai LI, Xin YIN, Han-ting FAN, Rong LI, Zhi-wei ZHANG, Wei TANG, Hui-jie HUANG, Feng CHEN. Report on Cardiac Gross Pathologic Measurements of Sudden Cardiac Death in Adults [J]. Journal of Forensic Medicine, 2023, 39(1): 1-6.
[12]	Hui WU, Fang-fang LIU, Jun-da WU, Ying XIE. Research Progress on Estimation of Postmortem Interval Based on Ocular Tissues Structure [J]. Journal of Forensic Medicine, 2023, 39(1): 50-56.
[13]	Tian-pu WU, Jian-long MA, Xin-biao LIAO, Dong-chuan ZHANG, Kai-jun MA, Yan-geng YU, Long CHEN. Research Progress on Molecular Changes in Pulmonary Hypoxia and Cause of Death Identification in Mechanical Asphyxia [J]. Journal of Forensic Medicine, 2023, 39(1): 57-65.
[14]	Yu-qing JIA, Tian-qi WANG, Rui ZHAO, Bao-li ZHU, Zhi-peng CAO. Effects of Postmortem Hemolysis and Ultrafiltration on Creatinine Detection Results [J]. Journal of Forensic Medicine, 2022, 38(6): 697-701.
[15]	Lan YANG, Xin WANG, Yong NIU. Research Progress of DNA-Based Technologies for Postmortem Interval Estimation [J]. Journal of Forensic Medicine, 2022, 38(6): 747-753.

Expression of c-jun Protein after Experimental Rat Brain Concussion

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics