法医学杂志

法医学杂志 ›› 2001, Vol. 0 ›› Issue (1): 4-6+61.

• 论文 • 上一篇    下一篇

实验性轻度病毒性心肌炎的组织病理学观察

成建定,陈玉川,胡丙杰,张雨,曾家乐,刘奕   

  1. 中山医科大学法医病理教研室!广东广州 510080,中山医科大学法医病理教研室!广东广州 510080,中山医科大学法医病理教研室!广东广州 510080,东莞市公安局刑警支队!广东 511700) ,东莞市公安局刑警支队!广东 511700) ,东莞市公安局刑警支队!广东 511700)
  • 发布日期:2001-02-25 出版日期:2001-02-28

Histopathological observation of experimental slight viral myocarditis

CHENG JIANDING, ET AL. (DEPARTMENT OF FORENSIC PATHOLOGY, SUN YAT－ SEN UNIVERSITY OF MEDICAL SCIENCES, GUANGZHOU,GUANGDONG 510080)   

  • Online:2001-02-25 Published:2001-02-28

被引次数

8

摘要： 为探索轻度病毒性心肌炎的法医病理学诊断方法，以适量 Coxsackie B3病毒感染 Balb/c小鼠造成小鼠轻度病毒性心肌炎，对病鼠的心、肝、脾、肺、肾进行常规病理学检查。结果发现，心肌炎小鼠的各器官出现不同程度的病理改变。实验提示，病毒性心肌炎是一类多器官病变的疾病；对多器官进行病理学观察和综合分析是轻度病毒性心肌炎的组织病理学诊断的有效方法之一。

关键词: 病毒性心肌炎, 疾病模型, 动物, 病理学

Abstract: To study the diagnostic method of slight viral myocarditis in the field of forensic pathology, slight viral myocarditis model was induced in Balb/c murine by coxsackie virus B3. Organs of hearts, livers, spleens, lungs and kidneys were examined through routine pathological methods. Pathological changes at different levels of these organs were observed. The results indicated that viral myocarditis was a kind of disease with multiple organ alterations and that the pathological observation and comprehensive analysis of multiple organs was one of the useful methods for diagnosing slight viral myocarditis.

Key words: viral myocarditis, animal model, pathology