法医学杂志

法医学杂志 ›› 2005, Vol. 0 ›› Issue (3): 219-222+.

• 论文 • 上一篇    下一篇

全基因组扩增技术的法医学应用价值及其结果评价

邓建强,侯一平   

  1. 司法部司法鉴定科学技术研究所,四川大学华西基础医学与法医学院 上海200063 ,四川成都610041
  • 发布日期:2005-06-25 出版日期:2005-06-28

Practice Value of Whole Genome Amplification Technology to be Used in Forensic Science and Analysisof its Result

DENG JIAN-QIANG1, HOU YI-PING2 (1.INSTITUTE OF FORENSIC SCIENCE, MINISTRY OF JUSTICE, P.R.CHINA, SHANGHAI200063,CHINA; 2.INSTITUTE OF FORENSIC MEDICINE, SICHUAN UNIVERSITY, CHENGDU 610041, CHINA)   

  • Online:2005-06-25 Published:2005-06-28

被引次数

15

摘要： 微量模板DNA的分析,一直是法医学特别关注和急需解决的难题之一,近年发展起来的一系列技术为解决这一问题提供了新的可能途径,本文即对微量模板DNA分析技术的进展和目前逐步发展的全基因组扩增技术的法医学应用价值、结果评价进行浅议。

关键词: 法医学, DNA检验, 微量分析, 全基因组扩增

Abstract: Genetic analysis from forensic microsamples is a urgent, difficult task in forensic science, because it isfrequently limited by the amount of specimen available in forensic practice, much effort has been carried out toresolve this difficulty. Whole genome amplification (WGA) technology, which was developing quickly in theseyears, has been thought to be a powerful, reliable and efficient strategy in analysis of minute amount DNA onmany fields. In this review, we discuss its application in forensic science.

Key words: forensic medicine, DNA analysis, microassay, whole genome amplification