法医学杂志

法医学杂志 ›› 2004, Vol. 0 ›› Issue (3): 143-144.

• 论文 • 上一篇    下一篇

家兔急性胰腺炎死后不同时间眼玻璃体液淀粉酶变化

李兴彪,张海燕,邵黎明   

  1. 温州医学院法医学教研室,温州医学院附属二院检验科,温州市公安局法医室 浙江温州325027 ,浙江温州325027 ,浙江温州325027
  • 发布日期:2004-06-25 出版日期:2004-06-28

Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits

LI XING-BIAO,ZHANG HAI-YAN,SHAO LI-MING(DEPARTMENT OF FORENSIC MEDICINE,WENZHOU MEDICAL COLLEGE,WENZHOU325027,CHINA)   

  • Online:2004-06-25 Published:2004-06-28

被引次数

32

摘要： 目的探讨急性胰腺炎死后不同时间眼玻璃体液淀粉酶变化。方法用1%牛胆酸钠诱导家兔急性胰腺炎动物模型建立,于死后不同时间和正常对照组,观察其淀粉酶变化。结果家兔急性胰腺炎死后72h眼玻璃体液淀粉酶含量(x)与死亡时间(y)存在相关关系,并导出其二项式回归方程为y=8.7420+0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001)。可作为推定早期损伤时间的参考指标。结论家兔急性胰腺炎死后不同时间眼玻璃体液淀粉酶改变为法医早期死亡时间推断提供了灵敏客观的实验依据。

关键词: 死亡时间, 急性胰腺炎, 眼玻璃体液, 淀粉酶

Abstract: Objective To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.Methods To induce animal model of acute pan-creatitis with sodium taurocholate,observed concentration changes of amylase after different postmortem in-terval,then compared with normal.Results The concentration of amylase in vitreous humor of rabbit24h after death were related to postmortem interval significantly;The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420+0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001).Conclusion Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.

Key words: postmortem interval, acute pancreatitis, vitreous humor amylase