法医学杂志 ›› 2017, Vol. 33 ›› Issue (2): 125-128.DOI: 10.3969/j.issn.1004-5619.2017.02.004

• 论著 • 上一篇    下一篇

不同注意状态对视敏度ERP检测的影响

孟欢欢1,2,罗  斌2,特拉提·赛依提3,季萌萌2,陈溪萍2,史格非4,陶陆阳2   

  1. (1. 济宁医学院法医学与医学检验学院法医学专业,山东 济宁 272012; 2. 苏州大学医学部法医学系,江苏 苏州 215123; 3. 新疆警察学院刑侦系,新疆 乌鲁木齐 830011; 4. 司法部司法鉴定科学技术研究所 上海市法医学重点实验室 上海市司法鉴定专业技术服务平台,上海 200063)
  • 发布日期:2017-04-25 出版日期:2017-04-28
  • 通讯作者: 陈溪萍,女,主任法医师,硕士研究生导师,主要从事法医临床学研究;E-mail:xipingchen@suda.edu.cn 史格非,男,硕士,主检法医师,主要从事法医临床学鉴定与研究;E-mail:shigf@ssfjd.cn
  • 作者简介:孟欢欢(1988—),女,硕士研究生,主要从事法医临床学研究;E-mail:mhhlinda@163.com
  • 基金资助:

    十三五国家重点研发计划项目(2016YFC0800701);国家自然科学基金资助项目(81373251);国家高技术研究发展计划(863计划)资助项目(2015AA020503)

Effect of Different Attentional Conditions on ERP Detection of Visual Acuity

MENG HUAN-HUAN1,2, LUO BIN2, T?藜L?藜T·SIYIT3, JI MENG-MENG2, CHEN XI-PING2, SHI GE-FEI4, TAO LU-YANG2   

  1. (1. Department of Forensic Medicine, School of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining 272012, China; 2. Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, China; 3. Department of Investigation, Xinjiang Police College, Urumchi 830011, China; 4. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Science, Ministry of Justice, PRC, Shanghai 200063, China)
  • Online:2017-04-25 Published:2017-04-28

摘要: 目的 研究不同注意状态对视敏度相关视觉信息刺激所产生事件相关电位(event-related potential,ERP)成分的影响,为法医临床学视觉客观评价提供理论参考。 方法 以视敏度图标作为视觉信息刺激范式,以15名志愿者作为研究对象,嘱其在视觉刺激注意状态下对视敏度图标进行计数,在视觉刺激非注意状态下认真收听有声故事并在实验结束后回答故事相关问题,应用32导ERP系统记录两种不同注意状态下受试者ERP结果。 结果 在两种注意状态下,阈上视敏度图标均引出了P1和P300成分,但阈下刺激图标只引出P1成分,未引出P300波形;在阈上图标所引出的ERP波形中,视觉刺激注意时的P1、P300振幅高于非注意时P1、P300振幅。 结论 注意状态影响视敏度检测,P300成分也可以用于视觉刺激非注意状态下阈上及阈下视敏度水平的鉴别。

关键词: 法医学, 事件相关电位, 视敏度, P1, P300, 注意状态

Abstract: Objective To study the effect of different attentional conditions on the event-related potential (ERP) components generated by the visual information stimuli related to visual acuity, and provide a theoretical reference for clinical forensic visual objective evaluation. Methods With visual acuity optotypes as normal form of visual information stimuli, 15 volunteers as study subjects were supposed to account the visual acuity optotypes under the attentional condition of visual stimuli. Furthermore, the subjects were required to listen to the storytelling carefully under the non-attentional condition of visual stimuli, and after the examination, they needed to answer the story-related questions. All the EEG results of two different attentional conditions from the subjects were recorded by 32 channel ERP system. Results Under two attentional conditions, P1 and P300 components were evoked by the visual acuity optotypes on supra-threshold and threshold visual acuity levels, while only P1 component were evoked by the visual acuity optotypes on sub-threshold levels. In the ERP waveforms evoked by the visual acuity optotypes on supra-threshold, P1 and P300 amplitudes under attentional condition were larger than that under non-attentional condition. Conclusion Attentional conditions can influence the detection of visual acuity. P300 component can be used to distinguish the visual acuity levels with supra-threshold and sub-threshold under non-attentional condition.

Key words: forensic medicine, event-related potentials, visual acuity, P1, P300, attentional condition

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