Journal of Forensic Medicine

›› 2015, Vol. 31 ›› Issue (6): 441-444.DOI: 10.3969/j.issn.1004-5619.2015.06.007

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Analysis and Discussion on Calculating Likelihood Ratio of DNA Mixture

LIU YING1, REN HE2, GAO LIN-LIN3, SHI YAN4, CHEN CHONG4, LIU YA-CHENG1,4   

  1. 1. Criminal Investigation Division, Beijing Public Security Bureau, Beijing 100192, China; 2. Beijing Police College, Beijing 102202, China; 3. Institute of Criminal Science and Technology, Hangzhou Public Security Bureau, Hangzhou 310004, China; 4. Beijing Tongda Shoucheng Institute of Forensic Science, Beijing 100192, China
  • Online:2015-12-25 Published:2015-12-28

Abstract: Objective To analyze and discuss four methods of calculating likelihood ratio of DNA mixture. Methods In the case with CNAS-T0757 proficiency testing in 2013, the likelihood ratios were calculated and compared among four methods, including unrestricted combinatorial method, Clayton’s method, p2 principle method, and recommendations from ISFG. Results The likelihood ratios were maximum by Clayton’s method and recommendations from ISFG, followed by result of the unrestricted combinational method. The minimum likelihood ratio was obtained by p2 principle. Conclusion The unrestricted combinational method could give furthest consideration to both information preservation and appraiser protection.

Key words: forensic genetics, statistics, likelihood ratio, mixture samples

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