Journal of Forensic Medicine

›› 2016, Vol. 32 ›› Issue (3): 219-221.DOI: 10.3969/j.issn.1004-5619.2016.03.015

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Genetic Polymorphism of 24 Y-STR Loci in Dongxiang Ethnic Minority Male Residents in Gansu Province of China

LUO JI-HUAI1,2, SUN HONG-BING1,2, YANG XIN1,2, HA FEI1,2, ZHANG ZI-LONG1   

  1. （1. Key Laboratory of Evidence of Science and Technology Research and Application, Gansu Province, Lanzhou 730070, China; 2. Institute of Criminal Science and Technology, Lanzhou Public Security Bureau, Lanzhou 730030, China）
  • Online:2016-06-25 Published:2016-06-28
  • Contact: SUN Hong-bing, professor, major in forensic genetics; E-mail: sunhb.good@163.com
  • About author:LUO Ji-huai （1983—）, M.D, major in forensic genetics; E-mail: lanzhouDNA110@126.com
  • Supported by:

    the Youth Science and Technology Foundation of Gansu Province （1308RJYA059）, Technology research projects of Gansu Provincial Public Security （2016JSYJ01）, National Natural Science Foundation （81302622）.

Abstract: Objective To determine the genetic polymorphism of 24 Y-STR loci haplotype and investigate its application value in legal physical evidence. Methods AGCU Y24 kit and 3130xl Genetic Analyzer were used to detect the distribution of 24 Y-STR loci including DYS391, DYS389Ⅰ, DYS439, DYS389Ⅱ, DYS438, DYS643, DYS456, DYS458, DYS437, DYS635, DYS448, DYS527a/b, Y-GATA-H4, DYS447, DYS19, DYS392, DYS522, DYS393, DYS388, DYS390, DYS385a/b and DYS444 in 154 unrelated individuals of Dongxiang ethnic minority males in Gansu province of China. Results A total number of 153 haplotypes were detected in 154 samples, the haplotype diversity was 0.991 5 and the discrimination power was 0.994 0. Conclusion The 24 Y-STR loci system has high haplotype diversity and discrimination power.  

Key words: forensic genetics, polymorphism, genetic, Y chromosome, short tandem repeat sequences, haplotype, Gansu, Dongxiang Population

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