Abstract: Objective To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.Methods To induce animal model of acute pan-creatitis with sodium taurocholate,observed concentration changes of amylase after different postmortem in-terval,then compared with normal.Results The concentration of amylase in vitreous humor of rabbit24h after death were related to postmortem interval significantly;The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420+0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001).Conclusion Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.

Key words: postmortem interval, acute pancreatitis, vitreous humor amylase