Estimation of Postmortem Intervals by Using Terminal Deoxynucleotidyl Transferase

Abstract

Abstract: Objective To investigate the relationship between DNA degradeation and postmortem interval. Methods dUTP was transferred to 3′terminal of DNA by using terminal deoxynucleotidyl transferase(TDT), then the reminders of dUTP after experimental reaction, as indicator of quantity of DNA degradation, were detected. Results The reminders of dUTP were decreasing along with the postmortem interval. Conclusion Postmortem DNA degradation may be used in postmortem interval judgment.

Key words: terminal deoxynucleotidyl transferase (TdT), postmortem interval, DNA degradation

ZHAN LAN;ZHAO ZI-QIN;SHEN YI-WEN;ET AL. (DEPARTMENT OF FORENSIC MEDICINE;SHANGHAI MEDICAL COLLEGE;FUDAN UNIVERSITY;SHANGHAI 000;CHINA). Estimation of Postmortem Intervals by Using Terminal Deoxynucleotidyl Transferase[J]. , 2005, 0(2): 113-114.

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Estimation of Postmortem Intervals by Using Terminal Deoxynucleotidyl Transferase

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