Abstract: Objective To abtain the genetic polymorphisms data of eleven Y-chromosome STR loci in Yunnan Han population, and to evaluate its forensic application values, which will provide the base data for forensic application. Methods DYS391,DYS389Ⅰ,DYS439,DYS389Ⅱ,DYS438,DYS437,DYS19,DYS392,DYS393,DYS390 and DYS385a/b loci were amplified by using Powerplex?誖Y PCR amplification Kit and were analyzed by 310 genetic analyzer. 201 unrelated male individuals of Han population in Yunnan were investigated to determine the distributions of allele frequencies and haplotypes. Results 3,5,6,8,5,4,5,8,4,7 alleles were found across the Y-STR loci except DYS38556 haplotypes were found across DYS385a/b locus. The minimum GD value was 0.4273(DYS438),and the maximum was 0.9747(DYS385a/b). 175 haplotypes were found, of which 154 were unique, 16 were found in 2 individuals,5 were found in 3 individuals, and the observed haplotypes diversity value was 0.9984. Conclusion The 11 Y-STR loci are highly polymorphic and are suitable for forensic personal identification and paternity testing in Yunnan Han population .

Key words: Y-chromosome, short tandem repeat(STR), haplotype, genetic polymorphism