Abstract: Inductively coupled plasma-mass spectrometry （ICP-MS） is the most common technique for elements analysis at present. ICP-MS with high sensitivity and wide linear range can be applied to multi-elements analysis in blood and urine. This paper reviews the common means of sample pretreatment （direct dilution method and wet digestion method）, the method for correction of mass spectral interference and non-interference, the main influence factors of analysis results, and provides an outlook of the application of ICP-MS in forensic toxicological analysis.

Key words: forensic toxicology, inductively coupled plasma-mass spectrometry（ICP-MS）, review[publication type], elements, blood, urine