Abstract: Objective To investigate the genetic polymorphisms of 21 autosomal STR loci of Fujian Han population and evaluate the forensic application value of GlobalFilerTM Express kit. Methods Amplified with GlobalFilerTM Express kit, DNA samples were obtained from 741 unrelated individuals of Fujian Han population. The population genetics parameters of 21 autosomal STR loci were calculated. Results The 21 autosomal STR loci were found to be no deviation from Hardy-Weinberg equilibration （P>0.05） and relatively abundant in high polymorphism. Heterozygosity ranged from 0.589 to 0.914, power of discrimination ranged from 0.754 to 0.992, polymorphic information content ranged from 0.520 to 0.940, and power of exclusion ranged from 0.278 to 0.825. The SE33 locus was the highest degree in polymorphism. Conclusion The 21 STR loci of GlobalFilerTM Express kit have high value in discrimination power and can be useful in personal identification and paternity test in Fujian Han population.

Key words: forensic genetics, polymorphism, genetic, GlobalFilerTM Express kit, Fujian, Han nationality