›› 2002, Vol. 0 ›› Issue (1): 17-18.

• 论文 • Previous Articles     Next Articles

A study of genetic polymorphism of the STR loci D20S85 and D6S477 in Han population living in Wuhan

SONG HAI-YAN, YANG RONG-ZHI, YANG QING-EN,ET AL. (DEPARTMENT OF FORENSIC BIOLOGY, TONGJI MEDICAL COLLEGE OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY,WUHAN,HUBEI, 430030 )   

  • Online:2002-02-25 Published:2002-02-28

Abstract: Objective The genetic polymorphism of two STR loci, D20S85 and D6S477, were studied in 280 unrelated Chinese individuals in Wuhan. Methods The PCR amplified products were analyzed by PAGE and silver staining. Results 10 and 9 alleles were observed in these two STR loci, and the discriminating power (DP) were 0.9085 and 0.9127 respectively. No deviations from Hardy-Weinberg equilibrium were found. The two STR loci had been successfully applied to individual identification and paternity testing. Conclusion The results demonstrated that the two loci were useful for forensic identification.

Key words: PCR-STR, D20S85, D6S477, polymorphism