›› 2005, Vol. 0 ›› Issue (3): 174-176.

• 论文 • Previous Articles     Next Articles

Correlation between PMI and DNA Degradation of Costicartilage and Dental Pulp Cells in HumanBeing

LONG REN1,WANG WEI-PING2, XIONG PING1, ET AL. (1.DEPARTMENT OF FORENSIC MEDICINE, NANHUA UNIVERSI-TY, HENGYANG 421001,CHINA; 2.PEOPLE′S COURT OF HENGYANG, HENGYANG 421001,CHINA)   

  • Online:2005-06-25 Published:2005-06-28

Abstract: Objective To probe the correlation between the postmortem interval (PMI) and the DNA degradationof costicartilage and dental pulp cells in human being after death ,and to seek a new method for estimating PMI.Methods The image cytometry was used to measure the DNA degradation under different ambient temperatures(30- 35℃,15- 20℃) in 0- 15 days after death. Results The average DNA content of two kinds of tissue wasdegradated with the prolongation of PMI. But there was a plateau period of 0~4 days for dental pulp cells ofhuman being in 15~20℃.There was a high negative correlativity P<0.01 between the average DNA content andPMI. Conclusion PMI could be estimated accurately according to the DNA degradation of costicartilage anddental pulp cells in human being after death.

Key words: postmortem interval, dental pulp, costicartilage, DNA degradation