Abstract: Objective To estimate the application of prognosis evaluation of ulnar nerve injury by 1H-magnetic resonance spectroscopy （1H-MRS）. Methods The metabolites of first dorsal interossei （FDI） of two hands from 12 healthy volunteers and 1 volunteer with complete ulnar nerve injury were detected by 1H-MRS and the data were statistically analyzed. Results For the FDI of healthy adults, the female peaks area of extra-myocellular lipids （EMCL） was higher than the male （P<0.05）; There was no significant difference in Cho, Cr and intra-myocellular lipids （IMCL） between male and female （P>0.05）; There was no significant difference in all the peaks area between the left and right hand （P>0.05）. The EMCL peak of the injury side was higher than that of the healthy side, and the area of FDI was reduced in the volunteer with ulnar nerve injury. Conclusion Noninvasive and quantitative detection of 1H-MRS may be valuable for prognosis evaluation of peripheral nerve injury.

Key words: forensic medicine, magnetic resonance spectroscopy, 1H-MRS, ulnar nerve, first dorsal interosseous muscle