Abstract: αB-crystallin is the structural protein of vertebrate lens, which is widely expressed in non-lens tissue. As one of the heat shock protein family members, αB-crystallin possesses biological properties of molecular chaperones and anti-apoptotic effects. Multi-factor injuries, such as retinopathy, inflammation and nervous system diseases, have a closely relationship with αB-crystallin. This paper reviews the research progress of the expression and mechanism of αB-crystallin in retina and extraocular tissues and organs.

Key words: forensic medicine, α-crystallin B chain, review [publication type], retina