›› 2009, Vol. 0 ›› Issue (3): 184-186.

• 论文 • Previous Articles     Next Articles

The Evaluation of Identifiler~(TM) System in Paternity Testing

QUE TING-ZHI,YAN PIN-HUA,LIN YUAN,LIU YAN,LI LI(SHANGHAI KEY LABORATORY OF FORENSIC MEDICINE,INSTITUTE OF FORENSIC SCIENCE,MINISTRY OF JUSTICE,P.R.CHINA,SHANGHAI 200063,CHINA)   

  • Online:2009-06-25 Published:2009-06-28

Abstract: Objective To evaluate the power of IdentifilerTM System for paternity testing.Methods A total of 3 277 paternity testing cases were studied using IdentifilerTM System.The exclusion power and mutation rates of the IdentifilerTM System were analysed in the paternity testing.Results The cumulated power of exclusion was 0.999 998 827,and the cumulated discriminating power was 0.999 999 999 999 999 98,respectively.Of the 3 277 cases,paternity was confirmed in 2 863,but excluded in 347.Among this paternity testing,mutations involving a single STR locus were observed in 65 cases,while mutations involving 2 STR loci were observed in 2 cases.Conclusion The IdentifilerTM System is powerful and reliable for paternity testing.

Key words: forensic genetics, paternity testing, short tandem repeat, IdentifilerTM System