Abstract: Objective To evaluate the application value of Mentype Argus X-8 kit in Chinese population,and to gather the genetic data of the eight X-STR loci.Methods The X-STR of 177 blood samples of unrelated East China Han population and 104 duo paternity testing cases was typed using Mentype Argus X-8 kit.The allele frequency and genetic data of the eight loci were investigated.Results The PIC of the eight X-STR loci was between 0.445 4 and 0.918 7.Among them,DXS10135 and DXS10101 had the highest PIC and exclusion rate in paternity cases.The other seven loci showed no difference in sexrelated allele frequency except DXS7132.In addition,there were several new alleles detected including DXS10074(allele 15.3),DXS10101(allele 36) and DXS10134(allele 37.3).Conclusion Eight X-STR loci included in Mentype Argus X-8 kit are high polymorphic and valuable.

Key words: forensic genetics, X-STR, Mentype Argus X-8 kit, paternity testing