The Impact of STR Mutations on Kinship Identification

doi:10.12116/j.issn.1004-5619.2024.541008

Abstract

Abstract:

Kinship identification is an important field of forensic genetics research, which can be widely applied in inheritance disputes, criminal investigations, and the identification of victims in major disaster cases. At present, capillary electrophoresis-based STR analysis is still the main method for kinship identification, but the impact of STR mutations on kinship identification needs further exploration. This paper reviews the theoretical basis and research status at home and abroad of kinship identification. The challenge of STR mutation impact on kinship identification is prospected, and possible solutions are discussed in order to obtain a regular understanding of the impact of STR mutation on kinship identification and improve the accuracy of kinship analysis.

Key words: forensic genetics, kinship identification, STR mutation, genetic marker, analysis method, review

CLC Number:

Jing LIU, Zheng WANG, Yi-ping HOU, Lin-chuan LIAO. The Impact of STR Mutations on Kinship Identification[J]. Journal of Forensic Medicine, 2024, 40(5): 484-491.

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