法医学杂志

法医学杂志 ›› 2005, Vol. 21 ›› Issue (2): 152-154+.

• 论文 • 上一篇    下一篇

吗啡依赖相关的酶学研究进展

洪仕君   

  1. 昆明医学院法医学院 云南昆明650031
  • 发布日期:2005-04-25 出版日期:2005-04-28

The Development of Research on Enzymes Related to Morphine-Dependent

HONG SHI-JUN(THE FACULTY OF FORENSIC MEDICINE,KUNMING MEDICAL COLLEGE, KUNMING 650031,CHINA)   

  • Online:2005-04-25 Published:2005-04-28

摘要： 吗啡依赖形成的机制是一个复杂的过程。涉及特定脑区突触超微结构变化、神经递质、酶学等多种复杂的机制,并且相互之间有密切的联系。本文从蛋白激酶类、一氧化氮合酶、超氧化物歧化酶、腺苷酸环化酶、琥珀酸脱氢酶、3β-羟基类固醇脱氢酶等几方面对吗啡依赖相关酶体系的研究进展作一综合性论述。

关键词: 吗啡依赖, 酶学, 机制

Abstract: The mechanism of morphine dependent is a complex Procedure. It involves in many complex mechanisms such as the ultra-structure of synapse of special brain areas, neurotransmitter,enzymology, and so on. These mechanisms have closely correlation. In this paper we reveiwed the development in enzymological mechanism of morphine dependent enzymes including protein kinase (PK), nitric oxide synthase (NOS) ,superoxide dismutase (SOD),adenylate cyclase (AC), Succinate dehydrogenase (SDH)and 3β-Hydroxy steroid dehydrogenase (3β-HSD).

Key words: morphine-dependent, enzymology, mechanism