法医学杂志 ›› 2021, Vol. 37 ›› Issue (6): 763-775.DOI: 10.12116/j.issn.1004-5619.2021.310202

所属专题: 合成毒品的法医毒理学研究

• 合成毒品的法医毒理学研究专题 • 上一篇    下一篇

甲基苯丙胺滥用现状及相关研究进展

洪仕君1(), 沈宝玉1, 孙荣基2, 杨根梦1, 段春梅2, 聂倩云1, 张从斌2, 董文娟1, 于浩1, 王上1, 刘鹏亮1, 闻品渊2(), 李利华1()   

  1. 1.昆明医科大学法医学院,云南 昆明 650500
    2.云南省药物依赖防治研究所,云南 昆明 650000
  • 收稿日期:2021-02-01 发布日期:2021-12-25 出版日期:2021-12-28
  • 通讯作者: 闻品渊,李利华
  • 作者简介:闻品渊,男,主要从事药物依赖防治及相关研究;E-mail:773597347@qq.com
    李利华,男,教授,主要从事毒品滥用毒理损害机制研究;E-mail:lilihua1229@126.com
    洪仕君(1974—),男,博士,教授,主要从事毒品滥用毒理损害机制研究;E-mail:kmhongshijun@126.com
  • 基金资助:
    国家自然科学基金资助项目(81760337);云南省创新团队资助项目(2017HC007);昆明医科大学科技创新团队资助项目(CXTD201604)

Current Situation of Methamphetamine Abuse and Related Research Progress

Shi-jun HONG1(), Bao-yu SHEN1, Rong-ji SUN2, Gen-meng YANG1, Chun-mei DUAN2, Qian-yun NIE1, Cong-bin ZHANG2, Wen-juan DONG1, Hao YU1, Shang WANG1, Peng-liang LIU1, Pin-yuan WEN2(), Li-hua LI1()   

  1. 1.School of Forensic Medicine, Kunming Medical University, Kunming 650500, China
    2.Yunnan Institute for Drug Abuse, Kunming 650000, China
  • Received:2021-02-01 Online:2021-12-25 Published:2021-12-28
  • Contact: Pin-yuan WEN,Li-hua LI

摘要:

毒品问题是世界性的重大社会公共安全问题,毒品滥用给经济发展、社会稳定和人民健康带来巨大威胁。近年来,以甲基苯丙胺为代表的合成毒品滥用已超过吗啡、海洛因、氯胺酮等传统毒品,成为世界范围内滥用最多的毒品之一。为解决毒品滥用这一重大社会公共安全问题,开展全方位、多层次的毒品相关问题的科学研究具有重要的理论价值和实践意义。本文立足当前毒品滥用形势,对合成毒品甲基苯丙胺滥用的流行病学特征、监测技术、毒性损害基础研究、戒断药物筛选、相关的临床共病以及检测技术等方面的研究进展进行综述,全面展现甲基苯丙胺滥用相关问题的发展趋势。

关键词: 法医毒理学, 成瘾, 甲基苯丙胺, 物质滥用, 共病, 综述

Abstract:

Drug problem is a major social and public security problem in the world. Drug abuse poses a great threat to economic development, social stability and public health. In recent years, synthetic drugs represented by methamphetamine have surpassed traditional drugs such as morphine, heroin, ketamine and become one of the most abused drugs in the world. In order to solve the problem of drug abuse, it is of great theoretical value and practical significance to carry out all-round and multi-level scientific research on drug-related issues. Based on the current situation of drug abuse, this article reviews research progresses on the epidemiology of methamphetamine abuse, the monitoring technology, the basic researches on toxicity damage, the withdrawal drug screening, the related clinical comorbidity and the testing technologies, comprehensively presenting the development trend of methamphetamine abuse related issues.

Key words: forensic toxicology, addiction, methamphetamine, substance abuse, comorbidity, review

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