›› 2014, Vol. 30 ›› Issue (3): 178-180.DOI: 10.3969/j.issn.1004-5619.2014.03.005

Previous Articles     Next Articles

Changes of Oscillatory Potentials of Electroretinogram after Methanol Intoxication in Rats

LIU DONG-MEI1,2, ZHOU SHU2,3, CHEN JIE-MIN2, PENG SHU-YA1,2, XIA WEN-TAO2   

  1. (1. Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, China; 2. Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, P.R. China, Shanghai 200063, China; 3. Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China)
  • Online:2014-06-25 Published:2014-06-28

Abstract: Objective To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats. Method The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room. Results The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule delayed approximately 16% and 61%, respectively. Conclusion The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.

Key words: forensic medicine, poisoning, methanol, electroretinogram, oscillatory potentials, rats

CLC Number: