A progress study on the relationship between postmortem interval and the changes of DNA content in the heart cellule of rat

Abstract

Abstract: Objective To study changes of DNA content in nuclear of the heart cellule of rats and relationship with the postmortem interval(PMI).Methods This experiment chose seven parameter of cell nuclear,including the area and integral optical density,determined the changes of DNA content in the heart cellule of15rats at different intervals between25and49h postmortem with the auto-TV-image system.Results The degradation rate of DNA in nuclear has a certainty relationship to the PMI a little later of rat.Conclusion Determining the quantity of DNA in nuclear should be an objective and exact way to estimate the PMI with the auto-TV-image system.

Key words: postmortem in terval, lmage analysis, rat, heart, DNA content

XU HONG-XIN ;LIU YA-LING ;DENG WEI-NIAN ;ET AL.(.SUPER PEOPLE'S COURT OF JIANGSU PROVINCE;NANJING00;.DEPARTMENT OF PEDIATRICS;WUHAN XIEHE HOSPITAL;TONGJI MEDICAL COLLEGE;HUAZHONG UNIVERSITY OF SCIENCE&TECHNOLOGY;WUHAN00). A progress study on the relationship between postmortem interval and the changes of DNA content in the heart cellule of rat[J]. , 2002, 18(4): 193-196.

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A progress study on the relationship between postmortem interval and the changes of DNA content in the heart cellule of rat

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