Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA

doi:10.12116/j.issn.1004-5619.2020.06.011

Journal of Forensic Medicine ›› 2020, Vol. 36 ›› Issue (6): 807-819.DOI: 10.12116/j.issn.1004-5619.2020.06.011

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Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA

LÜ Ye-hui1,2 , WANG Zhuo-qun1,2 , CHEN Yi-jiu2 , CHEN Long3

1. School of Basic Medical Sciences, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China; 2. Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China; 3. Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China

Received:2020-04-18 Online:2020-12-25 Published:2020-12-28

Abstract

Abstract: Postmortem interval （PMI） estimation has always been an important and difficult issue in the field of forensic pathology. In recent years, research progress on the estimation of PMI using RNA specific variation patterns after death has been made by researchers at home and aboard. This paper summarizes the specific application methods of messenger RNA and non-coding RNA for PMI estimation based on the literatures and discusses the existing problems and development trends, in order to provide technical reference for related studies and estimation practice

Key words: forensic pathology, estimation of postmortem interval, messenger RNA（mRNA）, non-coding RNA（ncRNA）, review

CLC Number:

DF795.1

LÜ Ye-hui, WANG Zhuo-qun, CHEN Yi-jiu , et al.. Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA[J]. Journal of Forensic Medicine, 2020, 36(6): 807-819.

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Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA

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