Research on the Genetic Polymorphisms of D6S2418 Locus in Chinese Han Ethnic, Thai and Germany Populations

Abstract

Abstract: Objective To obtain the genetic data on STR locus D6S2418,and analyzed its genetic polymorphism in 3 different races (Han,Thai and Germany). Methods The blood samples from 300 unrelated individuals were analyzed by PCR,PAG electrophoresis and silver staining. Results 9 alleles and 31 genotypes were observed.The observed heterozygosity and the discrimination power were 64%-81% and 84.2%-93.5%,respectively.The genotype distributions of D6S2418 locus in 3 populations were in accordance with Hardy-Weinberg equilibrium and the difference of allelic frequency distributions among 3 populations was obvious. Conclusion The methods founded are easy to perform and sensitive. The discrimination power and exclusion chances of this locus are desirable for forensic analysis and application.

Key words: short tandem repeat, PCR, D6S2418, genetic polymorphism

LIU ZHI-YONG;CHEN GUO-DI;REN GUANG-TIAN;ET AL. (. WEST CHINA SCHOOL OF PRECLINICAL AND FORENSIC MEDICINE;SICHUAN UNIVERSITY;CHENGDU 00;CHINA;. CENTER OF FORENSIC SCIENCES;PUBLIC SECURITY BUREAU OF YANTIAN DISTRICT;SHENZHEN 0;CHINA). Research on the Genetic Polymorphisms of D6S2418 Locus in Chinese Han Ethnic, Thai and Germany Populations[J]. , 2005, 0(4): 283-285.

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Research on the Genetic Polymorphisms of D6S2418 Locus in Chinese Han Ethnic, Thai and Germany Populations

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