›› 2010, Vol. 0 ›› Issue (1): 47-50.

• 论文 • Previous Articles     Next Articles

Applications of Alu Family in Forensic DNA Analysis

ZHAO GUI-SEN,CHANG LIN,MO YAO-NAN(1.KEY LABORATORY OF EVIDENCE SCIENCE,CHINA UNIVERSITY OF POLITICAL SCIENCE AND LAW,MINISTRY OF EDU-CATION,BEIJING 100088,CHINA;2.SCHOOL OF FORENSIC MEDICINE,HENAN UNIVERSITY OF SCIENCE AND TECHNOLO-GY,LUOYANG 471003,CHINA   

  • Online:2010-02-25 Published:2010-02-28

Abstract: Alu family is the primate specific short interspersed repetitive elements(SINEs).Its abundance and diversity distribution in genome,high methylation level and polymorphic for insertion make them ide-ally suitable as tools in forensic applications.The application of Alu sequence in forensic genomics,in-clude DNA quantitation,race determination,species and gender identification,personal identification,paternity testing and whole-genome amplification.The principles and characteristics of these Alu-based techniques are also summarized.The prospect of Alu as forensic molecular marker is discussed as well.

Key words: forensic genetics, Alu elements, review[publication type]