法医学杂志 ›› 2018, Vol. 34 ›› Issue (3): 286-293.DOI: 10.12116/j.issn.1004-5619.2018.03.014

• 综述 • 上一篇    下一篇

法医族源推断的分子生物学进展

孙  宽,侯一平   

  1. 四川大学华西基础医学与法医学院,四川 成都 610044
  • 发布日期:2018-06-25 出版日期:2018-06-28
  • 通讯作者: 侯一平,男,教授,主要从事法医物证学研究;E-mail:profhou@yahoo.com
  • 作者简介:孙宽(1989—),女,博士后,主要从事法医物证学研究;E-mail:daisydaisysun@163.com
  • 基金资助:
    国家自然科学基金资助项目(81571854)

Progress on Molecular Biology for Forensic Ancestry Inference

SUN Kuan, HOU Yi-ping   

  1. West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610044, China
  • Online:2018-06-25 Published:2018-06-28

摘要: 法医族源推断是将群体遗传学范畴的族源推断应用于法医学实践,协助案件的侦破和司法程序的顺利开展。随着基因组学的发展和广泛应用,DNA作为遗传信息的直接载体,很快替代各种表型层面的指标,成为法医族源推断的主要研究内容。本文对法医族源推断的各种遗传标记进行综述,同时对族源推断所采用的统计分析方法进行简述,进而对该领域的发展作一展望。

关键词: 法医遗传学, 生物学标记, 综述, 遗传标记, 分子生物学, 族源

Abstract: Forensic ancestry inference refers to the application of ancestry inference of population genetics in forensic practice, which aims to assist police investigation and judicial trial. With the rapid development and extensive use of genomics, DNA as a direct carrier of genetic information, has soon replaced various phenotypic markers and become the main research topics of forensic ancestry inference. This paper reviews different kinds of genetic markers used for forensic ancestry inference, the statistical analysis methods applied, and the prospects of the development in this field.

Key words: forensic genetics, biological markers, review, genetic markers, molecular biology, ancestry inference