Journal of Forensic Medicine ›› 2021, Vol. 37 ›› Issue (1): 69-76.DOI: 10.12116/j.issn.1004-5619.2020.400328

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Review and Prospects of Pathogen Detection Related to Autopsy of Coronavirus Infectious Diseases

WANG Yun-yi1 , ZHOU Nan1 , YUE Jia-cheng1 , ZHANG Kai1 , ZHAO Qian-hao1 , ZHENG Da1 , HU Bingjie2 , CHENG Jian-ding1   

  1. 1. Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China; 2. Department of Pathology, Guangzhou Medical University, Guangzhou 511436, China
  • Received:2020-03-31 Online:2021-02-25 Published:2021-02-28

Abstract: In the past, coronavirus caused two serious human-to-human pandemics in the world, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome(MERS). In late 2019, coronavirus disease 2019 (COVID- 19) caused another major global public health event. Due to the strong infectivity of novel coronavirus, it is difficult to carry out the autopsy of related death cases widely. This paper reviews the previous status of the pathogen detection related to the autopsy of coronavirus infection diseases, and introduces the ongoing detection methods of novel coronavirus in clinical practice, in order to provide reference for the pathogen detection and study related to autopsy of COVID-19.

Key words: forensic pathology, coronavirus, coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome, Middle East respiratory syndrome, autopsy, pathogen detection, review

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