法医学杂志

法医学杂志 ›› 2018, Vol. 34 ›› Issue (6): 611-616.DOI: 10.12116/j.issn.1004-5619.2018.06.007

所属专题： 法医毒物学新技术

• 专题 • 上一篇    下一篇

新型策划药甲卡西酮的法医毒理学研究现状

邓燕飞1，刘  良1，杨智曦2，梁  曼1   

  1. 1. 华中科技大学同济医学院法医学系，湖北 武汉 430030； 2. 重庆市人口和计划生育科学技术研究院 国家卫生计生委出生缺陷与生殖健康重点实验室 重庆市正鼎司法鉴定所，重庆 400020
  • 发布日期:2018-12-25 出版日期:2018-12-28
  • 通讯作者: 通信作者：梁曼，女，博士，主要从事法医毒理学研究；E-mail：liangman@hust.edu.cn 通信作者：杨智曦，男，主要从事法医病理学和法医临床学研究；E-mail：iamyangzhixi@163.com
  • 作者简介:邓燕飞（1991—），女，硕士研究生，主要从事法医病理学及法医毒理学研究与鉴定；E-mail：dengyanfei7057@sina.com
  • 基金资助:
    国家自然科学基金资助项目（81501632）

Research Status of New Designer Drug Methcathinone in Forensic Toxicology

DENG Yan-fei1, LIU Liang1, YANG Zhi-xi2, LIANG Man1   

  1. 1. Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; 2. Chongqing Zhengding Judicial Identification Institute, Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, China
  • Online:2018-12-25 Published:2018-12-28

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摘要： 卡西酮类新型策划药甲卡西酮与苯丙胺类药物结构相似，具有中枢神经兴奋作用，近年来被大肆滥用，致残、致死案例在国内外均有报道，引起广泛关注。甲卡西酮中毒症状主要为心动加速、高温、焦虑、抑郁等，国内外对其毒性机制的法医学研究甚少。本文就其毒理作用、中毒症状、中毒及成瘾机制、检测方法进行综述，为其进一步研究提供理论参考，为相关法医学鉴定提供借鉴。

关键词: 法医毒理学, 甲卡西酮, 策划药, 综述

Abstract: Methcathinone, a new cathinone designer drug, which is structurally similar to amphetamine analogs, is a central nervous stimulant. Recently, there has been a worldwide rise in its popularity and abuse, and a growing number of cases with disability or even death is reported in several countries, resulting in public concern. The typical symptoms include accelerated heartbeat, high temperature, anxiety, depression, etc. Forensic studies on its toxicity mechanism are rare. This article reviews its toxicological effects, poisoning symptoms, poisoning and addiction mechanisms, and detection methods, to provide theoretical reference for future studies and guidance for related forensic identification.

Key words: forensic toxicology, methcathinone, designer drug, review